Cognitive dysfunction in early experimental metabolic dysfunction-associated steatotic liver disease is associated with systemic inflammation and neuroinflammation

Cognitive dysfunction in early experimental metabolic dysfunction-associated steatotic liver disease is associated with systemic inflammation and neuroinflammation

Background & Aims: Cognitive dysfunction is an increasingly recognised manifestation of metabolic dysfunction-associated steatotic liver disease (MASLD), but the mechanistic link remains unclear. The aim of this study was to investigate the hypothesis that experimental MASLD leads to cogniti...

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Main Authors: Kristoffer Kjærgaard, Anne Catrine Daugaard Mikkelsen, Anne M. Landau, Peter Lykke Eriksen, Stephen Hamilton-Dutoit, Nils Erik Magnusson, Majken Borup Thomsen, Fenghua Chen, Hendrik Vilstrup, Rajeshwar Prosad Mookerjee, Cecilie Bay-Richter, Karen Louise Thomsen
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:JHEP Reports
Subjects:
Non-alcoholic fatty liver disease
non-alcoholic steatohepatitis
liver-brain axis
hepatic encephalopathy
neuroscience
cognitive dysfunction
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555923003233

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http://www.sciencedirect.com/science/article/pii/S2589555923003233

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