Proenkephalin-A secreted by renal proximal tubules functions as a brake in kidney regeneration

Abstract Organ regeneration necessitates precise coordination of accelerators and brakes to restore organ function. However, the mechanisms underlying this intricate molecular crosstalk remain elusive. In this study, the level of proenkephalin-A (PENK-A), expressed by renal proximal tubular epitheli...

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Bibliographic Details
Main Authors: Chi Liu, Xiaoliang Liu, Zhongwei He, Jiangping Zhang, Xiaoqin Tan, Wenmin Yang, Yunfeng Zhang, Ting Yu, Shuyi Liao, Lu Dai, Zhi Xu, Furong Li, Yinghui Huang, Jinghong Zhao
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42929-5