Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation

Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation

Abstract Background Neuroinflammation in spinal dorsal horn (SDH) plays an important role in the pathogenesis of interstitial cystitis/bladder pain syndrome (IC/BPS). Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) exert potent anti-inflammatory activities in the treatment of various...

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書目詳細資料
Main Authors: Chi Zhang, Yong Huang, Fubing Ouyang, Minzhi Su, Wenbiao Li, Jialiang Chen, Hengjun Xiao, Xiangfu Zhou, Bolong Liu
格式: Article
語言:English
出版: BMC 2022-04-01
叢編:Journal of Neuroinflammation
主題:
Interstitial cystitis/bladder pain syndrome
Mesenchymal stem cell
Extracellular vesicle
NLRP3 inflammasome
Neuroinflammation
在線閱讀:https://doi.org/10.1186/s12974-022-02445-7

因特網

https://doi.org/10.1186/s12974-022-02445-7

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