Dysregulation of the mRNA Expression of Human Renal Drug Transporters by Proinflammatory Cytokines in Primary Human Proximal Tubular Epithelial Cells
Proinflammatory cytokines, which are elevated during inflammation or infections, can affect drug pharmacokinetics (PK) due to the altered expression or activity of drug transporters and/or metabolizing enzymes. To date, such studies have focused on the effect of cytokines on the activity and/or mRNA...
| Hauptverfasser: | , , , , |
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| Format: | Artikel |
| Sprache: | English |
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MDPI AG
2024-02-01
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| Schriftenreihe: | Pharmaceutics |
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| Online Zugang: | https://www.mdpi.com/1999-4923/16/2/285 |