Chloroquine resistance is associated to multi-copy pvcrt-o gene in Plasmodium vivax malaria in the Brazilian Amazon

Chloroquine resistance is associated to multi-copy pvcrt-o gene in Plasmodium vivax malaria in the Brazilian Amazon

Abstract Background The resistance of Plasmodium vivax to chloroquine has become an obstacle to control strategies based on the use of anti-malarials. The current study investigated the association between P. vivax CQ-resistance in vivo with copy number variation and mutations in the promoter region...

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Bibliographic Details
Main Authors: Siuhelem Rocha Silva, Anne Cristine Gomes Almeida, George Allan Villarouco da Silva, Rajendranath Ramasawmy, Stefanie Costa Pinto Lopes, André Machado Siqueira, Gabriel Luíz Costa, Taís Nóbrega Sousa, José Luiz Fernandes Vieira, Marcus Vinícius Guimarães Lacerda, Wuelton Marcelo Monteiro, Gisely Cardoso de Melo
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Malaria Journal
Online Access:http://link.springer.com/article/10.1186/s12936-018-2411-5

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http://link.springer.com/article/10.1186/s12936-018-2411-5

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