Polygenic Hazard Score Associated Multimodal Brain Networks Along the Alzheimer’s Disease Continuum

BackgroundLate-onset Alzheimer’s disease (AD) is a polygenic neurodegenerative disease. Identifying the neuroimaging phenotypes behind the genetic predisposition of AD is critical to the understanding of AD pathogenesis. Two major questions which previous studies have led to are: (1) should the gene...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Kaicheng Li, Zening Fu, Shile Qi, Xiao Luo, Qingze Zeng, Xiaopei Xu, Peiyu Huang, Minming Zhang, Vince D. Calhoun
Format: Artikel
Sprache:English
Veröffentlicht: Frontiers Media S.A. 2021-09-01
Schriftenreihe:Frontiers in Aging Neuroscience
Schlagworte:
Online Zugang:https://www.frontiersin.org/articles/10.3389/fnagi.2021.725246/full