Association of SLC22A1, SLC47A1, and KCNJ11 polymorphisms with efficacy and safety of metformin and sulfonylurea combination therapy in Egyptian patients with type 2 diabetes

Association of SLC22A1, SLC47A1, and KCNJ11 polymorphisms with efficacy and safety of metformin and sulfonylurea combination therapy in Egyptian patients with type 2 diabetes

Background and purpose: Multidrug and toxin extrusion transporter 1 (MATE1), encoded by the SLC47A1 gene and single nucleotide polymorphisms of organic cation transport 1, may impact metformin's responsiveness and side effects. Inward-rectifier potassium channel 6.2 (Kir 6.2) subunits encoded b...

Full description

Bibliographic Details
Main Authors: Aya Ahmed, Hany M Elsadek, Sally M Shalaby, Hanan M Elnahas
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
metformin and sulfonylurea combination therapy; single nucleotide polymorphisms; type 2 diabetes mellitus.
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2023;volume=18;issue=6;spage=614;epage=625;aulast=Ahmed

Internet

http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2023;volume=18;issue=6;spage=614;epage=625;aulast=Ahmed

Similar Items