Association of SLC22A1, SLC47A1, and KCNJ11 polymorphisms with efficacy and safety of metformin and sulfonylurea combination therapy in Egyptian patients with type 2 diabetes

Association of SLC22A1, SLC47A1, and KCNJ11 polymorphisms with efficacy and safety of metformin and sulfonylurea combination therapy in Egyptian patients with type 2 diabetes

Background and purpose: Multidrug and toxin extrusion transporter 1 (MATE1), encoded by the SLC47A1 gene and single nucleotide polymorphisms of organic cation transport 1, may impact metformin's responsiveness and side effects. Inward-rectifier potassium channel 6.2 (Kir 6.2) subunits encoded b...

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Bibliographic Details
Main Authors:	Aya Ahmed, Hany M Elsadek, Sally M Shalaby, Hanan M Elnahas
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2023-01-01
Series:	Research in Pharmaceutical Sciences
Subjects:	metformin and sulfonylurea combination therapy; single nucleotide polymorphisms; type 2 diabetes mellitus.
Online Access:	http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2023;volume=18;issue=6;spage=614;epage=625;aulast=Ahmed

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