Interaction of human gut microbiota and local immune system in progression of colorectal adenoma (MIMICA-1): a protocol for a prospective, observational cohort study

Interaction of human gut microbiota and local immune system in progression of colorectal adenoma (MIMICA-1): a protocol for a prospective, observational cohort study

IntroductionThe current understanding of colorectal carcinogenesis is based on the adenoma-carcinoma sequence, where genetics, intestinal microbiota changes and local immunity shifts seem to play the key roles. Despite the emerging evidence of dysbiotic intestinal state and immune-cell infiltration...

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Main Authors: Jurate Valciukiene, Egle Lastauskiene, Aida Laurinaviciene, Matas Jakubauskas, Marius Kryzauskas, Ruta Barbora Valkiuniene, Renaldas Augulis, Ausra Garnelyte, Justinas Kavoliunas, Ugne Silinskaite, Tomas Poskus
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
gut microbiota
bacterial dysbiosis
intestinal immunity
colorectal polyps
colorectal adenoma
carcinoma in situ
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1495635/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1495635/full

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