Multicopy Single-Stranded DNA Directs Intestinal Colonization of Enteric Pathogens.

Multicopy single-stranded DNAs (msDNAs) are hybrid RNA-DNA molecules encoded on retroelements called retrons and produced by the action of retron reverse transcriptases. Retrons are widespread in bacteria but the natural function of msDNA has remained elusive despite 30 years of study. The major roa...

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Bibliographic Details
Main Authors: Johanna R Elfenbein, Leigh A Knodler, Ernesto S Nakayasu, Charles Ansong, Heather M Brewer, Lydia Bogomolnaya, L Garry Adams, Michael McClelland, Joshua N Adkins, Helene L Andrews-Polymenis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4569332?pdf=render