The protective antibodies induced by a novel epitope of human TNF-alpha could suppress the development of collagen-induced arthritis.

The protective antibodies induced by a novel epitope of human TNF-alpha could suppress the development of collagen-induced arthritis.

Tumor necrosis factor alpha (TNF-alpha) is a major inflammatory mediator that exhibits actions leading to tissue destruction and hampering recovery from damage. At present, two antibodies against human TNF-alpha (hTNF-alpha) are available, which are widely used for the clinic treatment of certain in...

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Bibliographic Details
Main Authors: Jie Dong, Yaping Gao, Yu Liu, Jinxia Shi, Jiannan Feng, Zhanguo Li, Heping Pan, Yanning Xue, Chuan Liu, Beifen Shen, Ningsheng Shao, Guang Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2811745?pdf=render

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http://europepmc.org/articles/PMC2811745?pdf=render

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