Asiatic acid reduces lipopolysaccharides-induced pulp inflammation through activation of nuclear factor erythroid 2-related factor 2 in rats

Background Dental pulp inflammation, often initiated by Gram-negative microorganisms and lipopolysaccharides (LPS), can lead to pulpitis and, subsequently, dental pulp necrosis, compromising tooth structure and increasing susceptibility to fracture. Asiatic acid, derived from Centella asiatica, has...

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Bibliographic Details
Main Authors: Risya Cilmiaty, Arlina Nurhapsari, Adi Prayitno, Annisa Aghnia Rahma, Muhana Fawwazy Ilyas
Format: Article
Language:English
Published: PeerJ Inc. 2024-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/18004.pdf