CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations

CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations

CryoEM structures and computational modeling of bovine anion exchanger 1 in both inward and outward facing conformations reveal an elevator-like mechanism of ion transport by a solute carrier ion transport family 4 member.

Bibliographic Details
Main Authors: Hristina R. Zhekova, Jiansen Jiang, Weiguang Wang, Kirill Tsirulnikov, Gülru Kayık, Hanif Muhammad Khan, Rustam Azimov, Natalia Abuladze, Liyo Kao, Debbie Newman, Sergei Yu. Noskov, D. Peter Tieleman, Z. Hong Zhou, Alexander Pushkin, Ira Kurtz
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-04306-8

Internet

https://doi.org/10.1038/s42003-022-04306-8

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