Identifying developability risks for clinical progression of antibodies using high-throughput in vitro and in silico approaches

ABSTRACTWith the growing significance of antibodies as a therapeutic class, identifying developability risks early during development is of paramount importance. Several high-throughput in vitro assays and in silico approaches have been proposed to de-risk antibodies during early stages of the disco...

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Bibliographic Details
Main Authors: Tushar Jain, Todd Boland, Maximiliano Vásquez
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:mAbs
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2023.2200540