Safety evaluation of a clinical focused ultrasound system for neuronavigation guided blood-brain barrier opening in non-human primates

Abstract An emerging approach with potential in improving the treatment of neurodegenerative diseases and brain tumors is the use of focused ultrasound (FUS) to bypass the blood–brain barrier (BBB) in a non-invasive and localized manner. A large body of pre-clinical work has paved the way for the gr...

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Bibliographic Details
Main Authors: Antonios N. Pouliopoulos, Nancy Kwon, Greg Jensen, Anna Meaney, Yusuke Niimi, Mark T. Burgess, Robin Ji, Alicia J. McLuckie, Fabian A. Munoz, Hermes A. S. Kamimura, Andrew F. Teich, Vincent P. Ferrera, Elisa E. Konofagou
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94188-3