The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice.

At least eight genotypes of Hepatitis B virus (HBV) have been identified. HBV genotype C is the most common genotype in Japan, although the incidence of HBV genotype A is increasing. The reason underlying the differences in viral multiplication of the HBV genotypes is unclear, especially in vivo. Th...

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Main Authors: Yoshinobu Yokoyama, Takuya Miyagi, Hayato Hikita, Teppei Yoshioka, Kaori Mukai, Takatoshi Nawa, Ryotaro Sakamori, Kazuyoshi Ohkawa, Naoki Hiramatsu, Takeshi Takahashi, Hiroshi Suemizu, Akihide Ryo, Tomohide Tatsumi, Tetsuo Takehara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4682774?pdf=render