Considerations and challenges for sex-aware drug repurposing

Considerations and challenges for sex-aware drug repurposing

Highlights Genetic, epigenetic, hormonal, immunological, metabolic, and environmental factors affect sex-biased drug responses. Drug repurposing approaches provide a significant advantage over novel drug development by reducing lengthy and costly clinical trials. Advances in compute processing power...

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Bibliographic Details
Main Authors: Jennifer L. Fisher, Emma F. Jones, Victoria L. Flanary, Avery S. Williams, Elizabeth J. Ramsey, Brittany N. Lasseigne
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Biology of Sex Differences
Subjects:
Sex differences
Drug repurposing
Sex-bias
Sex-aware
Review
Therapeutics
Online Access:https://doi.org/10.1186/s13293-022-00420-8

Internet

https://doi.org/10.1186/s13293-022-00420-8

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