Analysis of Amino Acid Mutations of the Foot-and-Mouth Disease Virus Serotype O Using both Heparan Sulfate and JMJD6 Receptors

Analysis of Amino Acid Mutations of the Foot-and-Mouth Disease Virus Serotype O Using both Heparan Sulfate and JMJD6 Receptors

Foot-and-mouth disease (FMD) is an economically devastating animal disease. Adapting the field virus to cells is critical to the vaccine production of FMD viruses (FMDV), and heparan sulfate (HS) and Jumonji C-domain-containing protein 6 (JMJD6) are alternative receptors of cell-adapted FMDV. We per...

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Bibliographic Details
Main Authors: Gyeongmin Lee, Ji-Hyeon Hwang, Aro Kim, Jong-Hyeon Park, Min Ja Lee, Byounghan Kim, Su-Mi Kim
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
foot-and-mouth disease virus
adaptation
receptor
heparan sulfate
JMJD6
vaccine seed virus
Online Access:https://www.mdpi.com/1999-4915/12/9/1012

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https://www.mdpi.com/1999-4915/12/9/1012

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