Rapid mechanical phenotyping of breast cancer cells based on stochastic intracellular fluctuations

Summary: Predicting the phenotypic impact of genetic variants and treatments is crucial in cancer genetics and precision oncology. Here, we have developed a noise decorrelation method that enables quantitative phase imaging (QPI) with the capability for label-free noninvasive mapping of intracellula...

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Bibliographic Details
Main Authors: Álvaro Cano, Marina L. Yubero, Carmen Millá, Verónica Puerto-Belda, Jose J. Ruz, Priscila M. Kosaka, Montserrat Calleja, Marcos Malumbres, Javier Tamayo
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224021850