Site-Specific Antibody–Drug Conjugates in Triple Variable Domain Fab Format

The interest in replacing the conventional immunoglobulin G (IgG) format of monoclonal antibodies (mAbs) and antibody–drug conjugates (ADCs) with alternative antibody and antibody-like scaffolds reflects a need to expand their therapeutic utility and potency while retaining their exquisite specifici...

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Bibliographic Details
Main Authors: Dobeen Hwang, Christoph Rader
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/5/764