SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer

SUMOylation of SMAD4 by PIAS1 in Conjunction with Vimentin Upregulation Promotes Migration Potential in Non-Small Cell Lung Cancer

Background: The expression of vimentin as a marker of epithelial-to-mesenchymal transition (EMT) has been speculated to be associated with tissue heterogeneity and metastases of non-small cell lung cancer (NSCLC). Methods: This study utilized in vitro co-immunoprecipitation with small interfering RN...

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Bibliographic Details
Main Authors: Chunli Wu, Xiaoxiao Zhu, Qi Dai, Zanbo Chu, Sijia Yang, Zhaoxing Dong
Format: Article
Language:English
Published: IMR Press 2023-08-01
Series:Frontiers in Bioscience-Landmark
Subjects:
non-small cell lung cancer
sumoylation
smad4
pias1
vimentin
Online Access:https://www.imrpress.com/journal/FBL/28/8/10.31083/j.fbl2808192

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https://www.imrpress.com/journal/FBL/28/8/10.31083/j.fbl2808192

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