High-Intensity Interval Cycle Ergometer Training in Parkinson's Disease: Protocol for Identifying Individual Response Patterns Using a Single-Subject Research Design

High-Intensity Interval Cycle Ergometer Training in Parkinson's Disease: Protocol for Identifying Individual Response Patterns Using a Single-Subject Research Design

Background: People with Parkinson's disease (PD) experience not only motor problems but also non-motor problems that seriously impede their daily functioning and quality of life. The current pharmacologic treatment of PD is symptomatic, and alternative rehabilitation treatments, which preferabl...

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Bibliographic Details
Main Authors: Erwin E. H. van Wegen, Mark A. Hirsch, Wilma D. J. van de Berg, Chris Vriend, Marc B. Rietberg, Mark A. Newman, Tim Vanbellingen, Odile A. van den Heuvel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
high intensity (strenuous) exercise
neuroplastic changes
BDNF
NFL
synuclein alpha
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.569880/full

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https://www.frontiersin.org/articles/10.3389/fneur.2020.569880/full

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