Anti-proliferative and apoptotic effect of cannabinoids on human pancreatic ductal adenocarcinoma xenograft in BALB/c nude mice model

Anti-proliferative and apoptotic effect of cannabinoids on human pancreatic ductal adenocarcinoma xenograft in BALB/c nude mice model

Abstract Human pancreatic ductal adenocarcinoma (PDAC) is a highly malignant and lethal tumor of the exocrine pancreas. Cannabinoids extracted from the hemp plant Cannabis sativa have been suggested as a potential therapeutic agent in several human tumors. However, the anti–tumor effect of cannabino...

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Bibliographic Details
Main Authors: Trung Quang Le, Nuntana Meesiripan, Suleeporn Sanggrajang, Nuntakan Suwanpidokkul, Piyaporn Prayakprom, Chatchada Bodhibukkana, Vipada Khaowroongrueng, Kankanit Suriyachan, Somchai Thanasitthichai, Attasit Srisubat, Pattamaporn Surawongsin, Anudep Rungsipipat, Siriwan Sakarin, Kasem Rattanapinyopituk
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Anti-proliferation
Apoptosis
Cannabis
Nude mouse xenograft model
Pancreatic adenocarcinoma
Online Access:https://doi.org/10.1038/s41598-024-55307-y

Internet

https://doi.org/10.1038/s41598-024-55307-y

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