Expression of Estrogen Receptor Alpha and Evaluation of Histological Degeneration Scores in Fibroblasts of Hypertrophied Ligamentum Flavum: A Qualitative Study

Expression of Estrogen Receptor Alpha and Evaluation of Histological Degeneration Scores in Fibroblasts of Hypertrophied Ligamentum Flavum: A Qualitative Study

The most common spinal disorder in elderly is lumbar spinal stenosis (LSS), resulting partly from ligamentum flavum (LF) hypertrophy. Its pathophysiology is not completely understood. The present study wants to elucidate the role of estrogen receptor α (ER α) in fibroblasts of hypertrophied LF. LF s...

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Bibliographic Details
Main Authors: Christina C. Westhoff, Christian-Dominik Peterlein, Hanna Daniel, Juergen R. Paletta, Roland Moll, Annette Ramaswamy, Stefan Lakemeier
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biomolecules
Subjects:
ligamentum flavum
hypertrophy
lumbar spinal stenosis
estrogen receptor alpha
fibrosis
degeneration
Online Access:https://www.mdpi.com/2218-273X/11/12/1752

Internet

https://www.mdpi.com/2218-273X/11/12/1752

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