Availability of Arg, but Not tRNA, Is a Rate-Limiting Factor for Intracellular Arginylation

Protein arginylation, mediated by arginyltransferase ATE1, is a posttranslational modification of emerging biological importance that consists of transfer of the amino acid Arg from tRNA to protein and peptide targets. ATE1 can bind tRNA and exhibits specificity toward particular tRNA types, but its...

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Bibliographic Details
Main Authors: Irem Avcilar-Kucukgoze, Brittany MacTaggart, Anna Kashina
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/1/314