Mechanisms Underlying Pioglitazone-Mediated Relaxation in Isolated Blood Vessel

Pioglitazone is a widely used anti-type 2 diabetic drug. Beside its insulin-sensitizing effects, pioglitazone exerts preventive roles against ischemic heart disease. Since one possible explanation is anti-hypertensive action, we examined effects of pioglitazone on contractility of isolated blood ves...

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Bibliographic Details
Main Authors: Hidemi Nomura, Hideyuki Yamawaki, Masashi Mukohda, Muneyoshi Okada, Yukio Hara
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319313325