Genetic Changes in Mastocytes and Their Significance in Mast Cell Tumor Prognosis and Treatment

Mast cell tumors are a large group of diseases occurring in dogs, cats, mice, as well as in humans. Systemic mastocytosis (SM) is a disease involving the accumulation of mast cells in organs. <i>KIT</i> gene mutations are very often seen in abnormal mast cells. In SM, high KIT/CD117 expr...

Full description

Bibliographic Details
Main Authors: Szymon Zmorzynski, Aleksandra Kimicka-Szajwaj, Angelika Szajwaj, Joanna Czerwik-Marcinkowska, Jacek Wojcierowski
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/15/1/137