Analysis of T and B Cell Epitopes to Predict the Risk of de novo Donor-Specific Antibody (DSA) Production After Kidney Transplantation: A Two-Center Retrospective Cohort Study

Analysis of T and B Cell Epitopes to Predict the Risk of de novo Donor-Specific Antibody (DSA) Production After Kidney Transplantation: A Two-Center Retrospective Cohort Study

Risk prediction of de novo donor specific antibody (DSA) would be very important for long term graft outcome after organ transplantation. The purpose of this study was to elucidate the association of eplet mismatches and predicted indirectly recognizable HLA epitopes (PIRCHE) scores with de novo DSA...

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Bibliographic Details
Main Authors: Shintaro Sakamoto, Kenta Iwasaki, Toshihide Tomosugi, Matthias Niemann, Eric Spierings, Yuko Miwa, Kosei Horimi, Asami Takeda, Norihiko Goto, Shunji Narumi, Yoshihiko Watarai, Takaaki Kobayashi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
kidney transplantation
eplet mismatch
PIRCHE-II
donor specific antibody
epitope analysis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02000/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02000/full

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