Synthesis and Assessment of the In Vitro and Ex Vivo Activity of Salicylate Synthase (Mbti) Inhibitors as New Candidates for the Treatment of Mycobacterial Infections

Synthesis and Assessment of the In Vitro and Ex Vivo Activity of Salicylate Synthase (Mbti) Inhibitors as New Candidates for the Treatment of Mycobacterial Infections

Tuberculosis (TB) causes millions of deaths every year, ranking as one of the most dangerous infectious diseases worldwide. Because several pathogenic strains of <i>M. tuberculosis</i> (<i>Mtb</i>) have developed resistance against most of the established anti-TB drugs, new t...

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Bibliographic Details
Main Authors: Matteo Mori, Giovanni Stelitano, Anna Griego, Laurent R. Chiarelli, Giulia Cazzaniga, Arianna Gelain, Elena Pini, Marina Camera, Paola Canzano, Andrea Fumagalli, Edoardo Scarpa, Chiara Cordiglieri, Loris Rizzello, Stefania Villa, Fiorella Meneghetti
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceuticals
Subjects:
tuberculosis
mycobactins
furan
siderophores
drug development
drug resistance
Online Access:https://www.mdpi.com/1424-8247/15/8/992

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https://www.mdpi.com/1424-8247/15/8/992

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