Contribution of Trp63CreERT2-labeled cells to alveolar regeneration is independent of tuft cells

Contribution of Trp63CreERT2-labeled cells to alveolar regeneration is independent of tuft cells

Viral infection often causes severe damage to the lungs, leading to the appearance of ectopic basal cells (EBCs) and tuft cells in the lung parenchyma. Thus far, the roles of these ectopic epithelial cells in alveolar regeneration remain controversial. Here, we confirm that the ectopic tuft cells ar...

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Bibliographic Details
Main Authors: Huachao Huang, Yinshan Fang, Ming Jiang, Yihan Zhang, Jana Biermann, Johannes C Melms, Jennifer A Danielsson, Ying Yang, Li Qiang, Jia Liu, Yiwu Zhou, Manli Wang, Zhihong Hu, Timothy C Wang, Anjali Saqi, Jie Sun, Ichiro Matsumoto, Wellington V Cardoso, Charles W Emala, Jian Zhu, Benjamin Izar, Hongmei Mou, Jianwen Que
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-09-01
Series:eLife
Subjects:
tuft cells
alveolar regeneration
viral infection
lung regeneration
COVID-19
basal cells
Online Access:https://elifesciences.org/articles/78217

Internet

https://elifesciences.org/articles/78217

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