The evolution of constitutively active humoral immune defenses in Drosophila populations under high parasite pressure.

Both constitutive and inducible immune mechanisms are employed by hosts for defense against infection. Constitutive immunity allows for a faster response, but it comes with an associated cost that is always present. This trade-off between speed and fitness costs leads to the theoretical prediction t...

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Bibliographic Details
Main Authors: Shuyu Olivia Zhou, Ramesh Arunkumar, Amina Irfan, Shuai Dominique Ding, Alexandre B Leitão, Francis M Jiggins
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011729&type=printable