Long-term exposure to copper induces mitochondria-mediated apoptosis in mouse hearts

Long-term exposure to copper induces mitochondria-mediated apoptosis in mouse hearts

Copper is a trace element necessary for the normal functioning of organisms, but excessive copper contents may be toxic to the heart. The goal of this study was to investigate the role of excessive copper accumulation in mitochondrial damage and cell apoptosis inhibition. In vivo, the heart copper c...

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Bibliographic Details
Main Authors: Ming Pan, Zi-wei Cheng, Chen-guang Huang, Zhu-qing Ye, Li-jun Sun, Hua Chen, Bei-bei Fu, Kai Zhou, Zhi-rui Fang, Zi-jian Wang, Qing-zhong Xiao, Xue-sheng Liu, Feng-qin Zhu, Shan Gao
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Copper
Cardiomyocytes
Mitochondria
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322001695

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http://www.sciencedirect.com/science/article/pii/S0147651322001695

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