Paroxysmal Nocturnal Hemoglobinuria: Biology and Treatment

Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant clonal hematopoietic disorder characterized by the lack of glycosylphosphatidylinositol-anchored proteins (GPI-APs) as a consequence of somatic mutations in the phosphatidylinositol glycan anchor biosynthesis class A (<i>PIGA</i>...

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Bibliographic Details
Main Authors: Carlos Bravo-Perez, Luca Guarnera, Nakisha D. Williams, Valeria Visconte
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/59/9/1612