Paroxysmal Nocturnal Hemoglobinuria: Biology and Treatment
Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant clonal hematopoietic disorder characterized by the lack of glycosylphosphatidylinositol-anchored proteins (GPI-APs) as a consequence of somatic mutations in the phosphatidylinositol glycan anchor biosynthesis class A (<i>PIGA</i>...
Main Authors: | Carlos Bravo-Perez, Luca Guarnera, Nakisha D. Williams, Valeria Visconte |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-09-01
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Series: | Medicina |
Subjects: | |
Online Access: | https://www.mdpi.com/1648-9144/59/9/1612 |
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