Lysine acetylation decreases enzyme activity and protein level of Escherichia coli lactate dehydrogenase

Lactate is an important bulk chemical with widespread applications and a major byproduct of other chemicals bioprocess in microbial fermentation. Lactate dehydrogenase A (LdhA) catalyzes the synthesis of lactate from pyruvate. Lysine acetylation is an evolutionarily conserved post-translational modi...

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Bibliographic Details
Main Authors: Min Liu, Meitong Huo, Likun Guo, Yingxin Fu, Mo Xian, Qingsheng Qi, Wei Liu, Guang Zhao
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Engineering Microbiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667370322000364