PATH-SURVEYOR: pathway level survival enquiry for immuno-oncology and drug repurposing

PATH-SURVEYOR: pathway level survival enquiry for immuno-oncology and drug repurposing

Abstract Pathway-level survival analysis offers the opportunity to examine molecular pathways and immune signatures that influence patient outcomes. However, available survival analysis algorithms are limited in pathway-level function and lack a streamlined analytical process. Here we present a comp...

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Bibliographic Details
Main Authors: Alyssa N. Obermayer, Darwin Chang, Gabrielle Nobles, Mingxiang Teng, Aik-Choon Tan, Xuefeng Wang, Y. Ann Chen, Steven Eschrich, Paulo C. Rodriguez, G. Daniel Grass, Soheil Meshinchi, Ahmad Tarhini, Dung-tsa Chen, Timothy I. Shaw
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Bioinformatics
Subjects:
Pathway-level survival analysis
R Shiny app
Hazard ratio GSEA
Pathway clustering
Online Access:https://doi.org/10.1186/s12859-023-05393-y

Internet

https://doi.org/10.1186/s12859-023-05393-y

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