Palmitic acid promotes miRNA release from adipocyte exosomes by activating NF-κB/ER stress

Abstract Objective The release of adipose tissue-derived miRNAs is increased under conditions of obesity, but the exact molecular mechanisms involved have not been elucidated. This study investigated whether obesity-induced increases in palmitic acid (PA) content could activate the NF-κB/endoplasmic...

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Bibliographic Details
Main Authors: Menghuan Li, Yanting Hou, Yao Chen, Chaoyue Sun, Maodi Liang, Xiaolong Chu, Xin Wen, Fangyuan Yuan, Chaoling Peng, Cuizhe Wang, Jianxin Xie, Jun Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2024-09-01
Series:Nutrition & Diabetes
Online Access:https://doi.org/10.1038/s41387-024-00334-x