CD5 Controls Gut Immunity by Shaping the Cytokine Profile of Intestinal T Cells

CD5 Controls Gut Immunity by Shaping the Cytokine Profile of Intestinal T Cells

CD5 is constitutively expressed on all T cells and is a negative regulator of lymphocyte function. However, the full extent of CD5 function in immunity remains unclear. CD5 deficiency impacts thymic selection and extra-thymic regulatory T cell generation, yet CD5 knockout was reported to cause no im...

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Bibliographic Details
Main Authors: Cornelia Schuster, Badr Kiaf, Teri Hatzihristidis, Anna Ruckdeschel, Janice Nieves-Bonilla, Yuki Ishikawa, Bin Zhao, Peilin Zheng, Paul E. Love, Stephan Kissler
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
T cell
costimulation
autoimmunity
cytokines
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.906499/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.906499/full

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