Prognostic and Predictive Value of p21-activated Kinase 6 Associated Support Vector Machine Classifier in Gastric Cancer Treated by 5-fluorouracil/Oxaliplatin Chemotherapy

Prognostic and Predictive Value of p21-activated Kinase 6 Associated Support Vector Machine Classifier in Gastric Cancer Treated by 5-fluorouracil/Oxaliplatin Chemotherapy

To determine whether p21-activated Kinase (PAK) 6 is a prognostic and predictive marker in gastric cancer (GC) and to construct a classifier that can identify a subset of patients who are highly sensitive to 5-fluorouracil/oxaliplatin chemotherapy. We retrospectively analyzed the expression levels o...

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Bibliographic Details
Main Authors: Yuming Jiang, Wei Liu, Tuanjie Li, Yanfeng Hu, Sile Chen, Sujuan Xi, Yajia Wen, Lei Huang, Liying Zhao, Cuicui Xiao, Xiaohui Huang, Zhen Han, Hao Liu, Xiaolong Qi, Yang Yang, Jiang Yu, Shirong Cai, Guoxin Li
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:EBioMedicine
Subjects:
Gastric cancer
p21-activated kinase 6
5-FU/oxaliplatin chemotherapy
SVM classifier
Nomogram
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417302633

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http://www.sciencedirect.com/science/article/pii/S2352396417302633

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