Prioritizing genes associated with brain disorders by leveraging enhancer-promoter interactions in diverse neural cells and tissues

Abstract Background Prioritizing genes that underlie complex brain disorders poses a considerable challenge. Despite previous studies have found that they shared symptoms and heterogeneity, it remained difficult to systematically identify the risk genes associated with them. Methods By using the CAG...

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Bibliographic Details
Main Authors: Xingzhong Zhao, Liting Song, Anyi Yang, Zichao Zhang, Jinglong Zhang, Yucheng T. Yang, Xing-Ming Zhao
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Genome Medicine
Subjects:
Online Access:https://doi.org/10.1186/s13073-023-01210-6