Characterization of the contribution of shared environmental and genetic factors to metabolic syndrome methylation heritability and familial correlations

Characterization of the contribution of shared environmental and genetic factors to metabolic syndrome methylation heritability and familial correlations

Abstract Background Transgenerational epigenetic inheritance has been posited as a possible contributor to the observed heritability of metabolic syndrome (MetS). Yet the extent to which estimates of epigenetic inheritance for DNA methylation sites are inflated by environmental and genetic covarianc...

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Bibliographic Details
Main Authors: Lindsay Fernández-Rhodes, Annie Green Howard, Ran Tao, Kristin L. Young, Mariaelisa Graff, Allison E. Aiello, Kari E. North, Anne E. Justice
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Genetics
Subjects:
Epigenetic inheritance
Methylation
Heritability
Familial correlation
Metabolic syndrome
Online Access:http://link.springer.com/article/10.1186/s12863-018-0634-7

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http://link.springer.com/article/10.1186/s12863-018-0634-7

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