Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism

Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism

Abstract N6-methyladenosine (m6A) is among the most abundant mRNA modifications, yet its cell-type-specific regulatory roles remain unclear. Here we show that m6A methyltransferase-like 14 (METTL14) differentially regulates transcriptome in brown versus white adipose tissue (BAT and WAT), leading to...

Full description

Bibliographic Details
Main Authors: Ling Xiao, Dario F. De Jesus, Cheng-Wei Ju, Jiang-Bo Wei, Jiang Hu, Ava DiStefano-Forti, Valeria Salerno Gonzales, Tadataka Tsuji, Siying Wei, Matthias Blüher, Yu-Hua Tseng, Chuan He, Rohit N. Kulkarni
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55694-w

Internet

https://doi.org/10.1038/s41467-024-55694-w

Similar Items