Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP

Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP

Abstract Background Among human T cell leukemia virus type 1 (HTLV-1)-infected individuals, there is an association between HTLV-1 tax subgroups (subgroup-A or subgroup-B) and the risk of HAM/TSP in the Japanese population. To investigate the role of HTLV-1 subgroups in viral pathogenesis, we studie...

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Bibliographic Details
Main Authors: Tadasuke Naito, Jun-ichirou Yasunaga, Yuichi Mitobe, Kazumasa Shirai, Hiroe Sejima, Hiroshi Ushirogawa, Yuetsu Tanaka, Tatsufumi Nakamura, Kousuke Hanada, Masahiro Fujii, Masao Matsuoka, Mineki Saito
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Retrovirology
Subjects:
HTLV-1
Virus subgroup
HAM/TSP
Tax
HBZ
Microarray
Online Access:http://link.springer.com/article/10.1186/s12977-018-0454-x

Internet

http://link.springer.com/article/10.1186/s12977-018-0454-x

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