Distinct gene expression signatures induced by viral transactivators of different HTLV-1 subgroups that confer a different risk of HAM/TSP
Abstract Background Among human T cell leukemia virus type 1 (HTLV-1)-infected individuals, there is an association between HTLV-1 tax subgroups (subgroup-A or subgroup-B) and the risk of HAM/TSP in the Japanese population. To investigate the role of HTLV-1 subgroups in viral pathogenesis, we studie...
Main Authors: | Tadasuke Naito, Jun-ichirou Yasunaga, Yuichi Mitobe, Kazumasa Shirai, Hiroe Sejima, Hiroshi Ushirogawa, Yuetsu Tanaka, Tatsufumi Nakamura, Kousuke Hanada, Masahiro Fujii, Masao Matsuoka, Mineki Saito |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
|
Series: | Retrovirology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12977-018-0454-x |
Similar Items
-
EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses
by: Tadasuke Naito, et al.
Published: (2019-12-01) -
The CC chemokine ligand (CCL) 1, upregulated by the viral transactivator Tax, can be downregulated by minocycline: possible implications for long-term treatment of HTLV-1-associated myelopathy/tropical spastic paraparesis
by: Mineki Saito, et al.
Published: (2017-12-01) -
Role of HTLV-1 Tax and HBZ in the Pathogenesis of HAM/TSP
by: Yoshimi Enose-Akahata, et al.
Published: (2017-12-01) -
Current Perspectives in Human T-Cell Leukemia Virus Type 1 Infection and Its Associated Diseases
by: Michi Miura, et al.
Published: (2022-04-01) -
HTLV-1 HBZ Protein Resides Exclusively in the Cytoplasm of Infected Cells in Asymptomatic Carriers and HAM/TSP Patients
by: Greta Forlani, et al.
Published: (2019-04-01)