Abnormalities in intron retention characterize patients with systemic lupus erythematosus

Abnormalities in intron retention characterize patients with systemic lupus erythematosus

Abstract Regulation of intron retention (IR), a form of alternative splicing, is a newly recognized checkpoint in gene expression. Since there are numerous abnormalities in gene expression in the prototypic autoimmune disease systemic lupus erythematosus (SLE), we sought to determine whether IR was...

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Bibliographic Details
Main Authors: Xiaoqian Sun, Zhichao Liu, Zongzhu Li, Zhouhao Zeng, Weiqun Peng, Jun Zhu, Joel Zhao, Chenghao Zhu, Chen Zeng, Nathaniel Stearrett, Keith A. Crandall, Prathyusha Bachali, Amrie C. Grammer, Peter E. Lipsky
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-31890-4

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https://doi.org/10.1038/s41598-023-31890-4

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