Antioxidant Effects of PS5, a Peptidomimetic of Suppressor of Cytokine Signaling 1, in Experimental Atherosclerosis

Antioxidant Effects of PS5, a Peptidomimetic of Suppressor of Cytokine Signaling 1, in Experimental Atherosclerosis

The chronic activation of the Janus kinase/signal transducer and activator of the transcription (JAK/STAT) pathway is linked to oxidative stress, inflammation and cell proliferation. Suppressors of cytokine signaling (SOCS) proteins negatively regulate the JAK/STAT, and SOCS1 possesses a small kinas...

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Bibliographic Details
Main Authors: Sara La Manna, Laura Lopez-Sanz, Susana Bernal, Luna Jimenez-Castilla, Ignacio Prieto, Giancarlo Morelli, Carmen Gomez-Guerrero, Daniela Marasco
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
mimetic peptides
cytokine signaling
JAK/STAT
suppressor of cytokine signaling 1 (SOCS1)
oxidative stress
atherosclerosis
Online Access:https://www.mdpi.com/2076-3921/9/8/754

Internet

https://www.mdpi.com/2076-3921/9/8/754

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