Integrative single-cell analysis of LUAD: elucidating immune cell dynamics and prognostic modeling based on exhausted CD8+ T cells

Integrative single-cell analysis of LUAD: elucidating immune cell dynamics and prognostic modeling based on exhausted CD8+ T cells

BackgroundThe tumor microenvironment (TME) plays a pivotal role in the progression and metastasis of lung adenocarcinoma (LUAD). However, the detailed characteristics of LUAD and its associated microenvironment are yet to be extensively explored. This study aims to delineate a comprehensive profile...

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Bibliographic Details
Main Authors: Han Zhang, Pengpeng Zhang, Xuefeng Lin, Lin Tan, Yuhang Wang, Xiaoteng Jia, Kai Wang, Xin Li, Daqiang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
LUAD
myeloid
CD4+ T cells
CD8+ T cells
pDCs
GALNT2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1366096/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1366096/full

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