A novel quinazolinone derivative induces cytochrome c interdependent apoptosis and autophagy in human leukemia MOLT-4 cells

A novel quinazolinone derivative induces cytochrome c interdependent apoptosis and autophagy in human leukemia MOLT-4 cells

Crosstalk between apoptosis and autophagy is budding as one of the novel strategies in the cancer therapeutics. The present study tinted toward the interdependence of autophagy and apoptosis induce by a novel quinazolinone derivative 2,3-dihydro-2-(quinoline-5-yl) quinazolin-4(1H)-one structure [DQQ...

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Bibliographic Details
Main Authors: Suresh Kumar, Santosh Kumar Guru, Anup Singh Pathania, Nagaraju Mupparapu, Ajay Kumar, Fayaz Malik, Sandip B. Bharate, Qazi Naveed Ahmed, Ram A. Vishwakarma, Shashi Bhushan
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Toxicology Reports
Subjects:
2,3-Dihydro-2-(quinoline-5-yl) quinazolin-4(1H)-one structure [DQQ]
Autophagy
Apoptosis
Cytochrome c
Caspase
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014000663

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http://www.sciencedirect.com/science/article/pii/S2214750014000663

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