Genetically predicted androgenic profiles and adverse cardiac markers: a sex‐specific Mendelian randomization study

Genetically predicted androgenic profiles and adverse cardiac markers: a sex‐specific Mendelian randomization study

Abstract Aims Observational evidence suggests associations between sex hormone levels and heart failure (HF). We used sex‐specific genetic variants associated with androgenic sex hormone profiles to investigate the causal relevance of androgenic sex hormone profiles on cardiac structure and function...

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Bibliographic Details
Main Authors: Jun Yu Chen, Maddalena Ardissino, Rohin K. Reddy, Amy Marie Mason, Zahra Raisi‐Estabragh, Emanuele Di Angelantonio, Stephen Burgess, Fu Siong Ng
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:ESC Heart Failure
Subjects:
SHBG
Testosterone
Sex hormones
Heart failure
CMR
Mendelian randomization
Online Access:https://doi.org/10.1002/ehf2.14527

Internet

https://doi.org/10.1002/ehf2.14527

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