Serum microRNA-122 and Wisteria floribunda agglutinin-positive Mac-2 binding protein are useful tools for liquid biopsy of the patients with hepatitis B virus and advanced liver fibrosis.

BACKGROUND:Noninvasive methods to accurately and conveniently evaluate liver fibrosis are desirable. MicroRNA (miR) is one of the candidates. MiRs are small RNAs consisting of 19-25 nucleotides that negatively regulate many target genes at transcriptional levels. Recently, many researchers have focu...

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Bibliographic Details
Main Authors: Masato Nakamura, Tatsuo Kanda, Xia Jiang, Yuki Haga, Koji Takahashi, Shuang Wu, Shin Yasui, Shingo Nakamoto, Osamu Yokosuka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5419651?pdf=render